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Works for me

Can you make a video on anafranil I have ice and I've been takong since 2014 I take 150 mh of anafranil is that too high of a dose I take the 3 of the 50 mg capsules release at bedtime it helps me sleep I like iy because it doesn't kill my sex drive like Lexapro did on 20 mg when I first got on anafranil it caused severe constipation but it doesn't have that side effect anymore I like anafranil It helps with my pure o ocd I still have obsessions but not compulsions but I like to obessed about my interest in excerise and looking good just please make a video on afranil what are your thoughts on it as a psychiatrist thank you

Klonopin helps me tremendously with GAD, and I have been on it for about 10 years at 3 mg. Would you cite the meta-analysis?

What is maximum proper dose fo sertraline when combined with buproprion? as they share at least one of the isozyme of CYP450 (not strong inhibition)

I have clean quite strong GAD, with very little or even no typical symptoms of depression, Buproprion makes me sleepy at the beginning when combined with SSRI :) while SSRI alone does not make me sleepy :D Those drugs are tricky, but there is one (uncertain) thing wich may happen when you take mild stimulants having anxiety. Of course in that case primary drug might be an SSRI, like Zoloft (but not in all cases). Sertraline always should be first choice as it it affects less hormones due to weak dopamine reuptake inhibitory. It is believed that too much serotonin over dopamine increases prolactine and some other hormones. When it comes to buproprion....Yes at the beginning it may increase your anxiety, but what about noradrenaline receptors downregulation after a time? that might be one of the positive pathway in reducing anxiety. It's kind of rebound effect as well. When you take benzodiazepines for a short period when addiction not happen, then rebound anxiety appears, as when you take downer then you stop it, you expect rebound effect. So maybe when you take mild safe stimulant the opposite thing take place :) I wonder if drinking coffee which would be unpleasent for anxious agitated people can downregulate receptors over time and when you stop drkinking it you would be calmer and sleepy :) Maybe it's all about receptors, when too little serotonine or dopamine (prolonged bad mood and stress affect that level and other negative compesatory reactions happen), the receptors become upregulated which is why you easily get anxious (especially when you take a pill which may be a bit stimulating) , when is proper amount of the neurotransmitters or even too much, if you take drugs which inhibits reuptake process, then receptors start to downregulate which makes you more stable or even a bit blunt if the effect is too strong. It is plasticity of brain. Of course this is very simplified it's much more tricky , complicated. Downregulation process sometimes is not good :) This is one of the reason you may feel the drug does not work as good as earlier over time and you must increase dosage. When you start drug and you do not feel too much adverse reactions (benzos should be added for first weeks when too much anxiety exists) you feel very good, even a bit euphoric. You wish to be like that for longer time, but compesatory reactions (downregulation and others) reduce that effect :) tricky thing....Additionally I believe that anxiety connected with hyper stuff, like hyperactivation, overreaction, too much negative energy which affect sleeping, may happen more often in people who were a bit hyper since they born... so I wonder if that mild hyper + anxiety is negative synergic effect and buproprion in that case may help as overtime it might reduce that small part of ADHD (many people may have very mild kind of ADHD that in normal circumstances are not treated with any stimulant)

No thiVortioxetine is the only antidepressant that improves cognitive functions, by acting like some older "dirty drugs" on many signaling substances and their receptors. The reason that patients feel clearer in their thinking is because vortioxetine increases the level of histamine, among other things. The impact of its positive effect on cognitive functions should certainly not be underestimated. Vortioxetine does not have a better antidepressant effect than regular SSRIs, but with the ability to make patients think more clearly, get better memory and counteract apathy and anhedonia, means that it is generally better in the end than usual SSRIs/SNRIs/TCAs. In addition, a big plus for the lack of annoying side effects. Of course, it will never help ALL patients with depression and/or anxiety, but many may benefit from it if they have already tried other antidepressants without good effect. The biggest disadvantage is that it is still very expensive.s video don't tell the truth. It is

Stay away from psychiatrists.

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Thank you! :)

Zoloft (taken for months) and added recently Wellbutrin makes me sleepy initially but it's good as I have strong GAD. Does it mean I may have kind of ADHD ? since mild stimulant makes me sleepy ? Since I've born I am a bit hyperactive (mild) BTW What is proper max. dose of sertraline when combined with buproprion? as those drugs affect metabolism (mild to moderate) of each other.

Is there really no contribution from DXM beyond the pharmacokinetic interaction? I know this is widely regarded to be the case, but I have yet to see definitive evidence to rule out the relevance of a pharmacodynamic interaction.

I love your channel!! I'm trying to do DYI. My insurance will only pay 650.00 per month leaving me having to pay 350.00 out of pocket. I hope this works for me. Nothing else, not even ketamine has. 😢

I took Sertraline for 5 months but nothing changed, now I'm starting escitalopram I hope it work

Hello Dr. Shrinks. I have been living with a diagnosis of chronic depression (dysthymia) for 4 years. I tried many medications but I couldn't get better. Today my doctor prescribed me California Rocket Fuel. (Venlafaxine 300 mg/day, Mirtazapine 15 mg/day and Abilify 5 mg/day). Do you think my depression will be completely cured after this combination of medications? What is the success rate of this combination in dysthymia? Thanks

Pharmagaba can cross the blood brain barrier. There is some evidence that L-Arginine helps gaba cross the blood brain barrier. Fiji kava is best for anxiety imo, but tastes bad and expensive

Your cousin Emily is a con

The one thing that makes sense is the reason on a map that it's so much more on the east coast of the United States is because 80% of the US population lives on the east half of the United State. Just like as the East Coast has around 90% of all railroads which ties to the history of the United States.

I hear the cold turkey comments and all, but what about the ones who want to stop but don't have 22days or 86days to go thru such a horrible feeling?!!❤

Bullshit. Works for me 100% of the time.

You are the best id like to have. An appoint with you

Hey Dr. Sneaker Shrink, just finished your series on California Rocket Fuel, and man, I feel like I’m back in my shrink’s chair getting bombarded with info. Any chance we could get a redo with clearer sound? No throwback cassette vibes, please! Also, how about packing it all into a snappy 15-minute video? Just hit us with the essentials like how it works, what to expect, and why it's called that. No need for a marathon session - if we're hungry for more, we can dive into those 15 other videos you've got. Keep it fun and light, like chatting with a buddy over coffee, not a lecture that tests our seat's comfort. Looking forward to something crisp and engaging. Cheers!

I'm in my 4th week of Spavato, I don't think I could handle the i.v.

I’ve been on these meds for four months now. The side effects the first two weeks were hell but now I feel great. I’m glad I did not follow the horror stories online. These meds work differently for everyone. You won’t know until you take them. Avoid drinking too much though because it can cause you agitation the next day.

Abilify made me extremely paranoid and super anxious! 😬 I told my psychiatrist what it was doing and she didn’t believe me. As soon as I stopped the medication, the paranoia stopped…

Abilify worsened my anxiety and made me extremely paranoid. I told my psychiatrist what it was causing and she didn’t believe me. As soon as I got off of Abilify the paranoia stopped.

Abilify made me extremely paranoid and worsened my anxiety. My psychiatrist didn’t believe me and as soon as I got off it the paranoia stopped….

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Thank you for making this video. I really appreciate 🙏🏼

And for depression!

Let me ask you Mr psychiatrist in sneakers. I f it stimulates the Mu receptor which you emphasize so much then why doesn’t it make me feel like I’ve just took Oxycodone?? Oxycodone is NOT a full agonist. It doesn’t occupy the receptor 100 percent. Both are derived from thebaine. Why don’t I feel the same way as if taking oxycodone?? Answer me that hot shit in sneakers. You are getting kick backs from pharmaceutical companies plain and simple you fraud Dr

Is very helpfull when you in bad way

Appreciate this video. I feel like there aren't enough resources on the comorbidity and pharmacological interventions tend to be written off. I was recently diagnosed with OCD in addition to existing BPAD dx. The OCD had become debilitating. Therapy was not an option for several reasons. Tried sertaline - mania followed. OCD reduced by 90%. Optimised lithium dose to bring into antimanic range. Continued lamotrigine and aripiprazole. Kept sertraline low. It all evened out and life is livable. It's definitely possible.

Has made my insomnia So. Much. Worse.

As someone who has suffered from suicidal ideation for many years, and who has been involuntarily comitted, I think suicide can be prevented by not removing lethal means. This is obvioualy anecdotal, but knowing that if things get really bad that you have a way out, gives you the strength to carry on for longer. The abuse that I endured in the psych ward did so much more damage than anything else in my life up to that point resulted in my only serious suicide attempt the same day I was released.

Yup yup, that's cool and all, but when can we expect an onlyfans?

Do you know how to calculate the blood level

An example of how my doctor and I decided to use extended vs immediate release was that my Adderall dosage was perfect strength, but the duration was too short. Other medications that last longer haven't worked as well with me. I didn't want a second extended dose after taking a 20mg, so we added a simple 5mg immediate release around lunch time.

Are there any low risk pain relief medications with high success rates that you could recommend?

I was prescribed gabapentin for chronic physical pain but I'm afraid to take due to potential side effects such as memory problems.

Bupropion is illegal in our country. Are there any alternatives for noradrenaline depression?

Once my ADHD son turns 18 and he doesn’t smarten up then he is more than welcome to join the homeless/street community. I am so tired of having to treat him special like his dietary preferences.

Don’t take this med. getting off it is hell. The benefits don’t outweigh the side effects.

Remicade actually can cause depression. Started Remicade March 2015, by August 2015, I was in a psychiatric facility for severe depression and anxiety. Eight years later in 2023, I broke out in severe psoriatic arthritis, I now also have lymphoma, and I’m fighting for my life. Beware.

Very helpful and clear. Thanks!

I had severe depression for years. I was referred to a Chinese doctor with a reputation for curing hard cases. She asked me about my diet. I told her that eggs gave me severe asthma attacks, and that this had never happened before. She wrote a prescription for three antibiotics. I thought she was nuts. I took them, and within three days I have never experienced depression ever again. It was due to bad gut bacteria, killed with antibiotics.

It works for me

Man in US i was on 3 suboxones a day and I came to Europe and they put me on only one. Holy shit was I SICK. I had to buy extra until I tappered down. Suboxone is no joke.. yes it helps you get your life in order but you better know what you are doing!!

I’m taking Fluoxetine 40 mg (Prodep) with bupropion 150 mg, for MDD and Trauma. Is it a good choice?

QUESTION please i was given Quviviq, after hrs i still did not fall asleep, two u meds u mentioned (orexon blocking drugs i thank the called) are all thew the same? if Quviviq doesn't help me sleep will the other two brands u mentioned like belsomra or the other one u mentioned might word better then Quviviq? (I had a stroke 6 months ago and have had insomnia ever since my stroke) my doctor even tried me on Ambien and lunesta (before my stroke Ambien always help me fall asleep the few times I needed it) however after my stroke Ambien and lunesta didn't help me fall asleep maybe a few hours if that! a strong amount of benzos is the only thing that helps me😢 but my doctor doesn't want me being on benzos forever😢 i dont know if u have any advice...i was given temazepam 9 of them and I didn't even sleep she even told me to take 30 mg! it did absolutely nothing to help me sleep. before the stroke I could sleep 18 hours a day if I needed or wanted to easily. but after my stroke and now for 6 months the only thing that helps me sleep is it good amount of. (2 mg of clonazepam but now sometimes that's not even enough!)

you said that psyciatrist prescribe 300 mg qutaipine foe deppression but mine prescribed only upto 50 mg once a day and continued it for like six months and then stopped it ,my question is why did he prescribed such a low dose more major deppressive disorder is there any other medical reason behind it ? please tell?